Unusual presentation of multiple myeloma with unilateral visual loss and numb chin syndrome in a young adult

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An unusual presentation of multiple myeloma with unilateral sudden vision loss

RATIONALE Plasma cell neoplasms are categorized by neoplastic proliferation of a single clone of plasma cells which produce a monoclonal immunoglobulin. Plasma cell neoplasms can present as a solitary plasmacytoma or as multiple myeloma. Both of them can progress to multiple myeloma. Once a diagnosis of plasmacytoma has been made, thorough examinations should be carried out for identifying the ...

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Numb chin syndrome.

CLINICAL HISTORY This 67-year-old man was seen in neurological consultation with a 10-day history of numbness and tingling of the right chin which was intermittent for the first 3 days and then constant for one week. The chin could also be intermittently painful with an intensity ranging from 7 to 9/10 especially with chewing. He had no headache, speech disturbance, dysphagia, visual disturbanc...

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Unusual presentation of ‘numb chin syndrome’ as the manifestation of metastatic adenocarcinoma of the lung☆

INTRODUCTION Numb chin syndrome (NCS) is the presence of hypoaesthesia or paraethesia of the lip and chin over the distribution of the mental nerve. It is often caused by the presence of a metastatic tumour in the mandible or the base of skull and represents advanced malignancy. PRESENTATION OF CASE This paper presents an unusual case of NCS associated with metastatic adenocarcinoma of the lu...

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Numb chin syndrome.

Numb chin syndrome reflects an abnormality in the mental nerve or inferior alveolar nerve, or occasionally in a nervous structure located higher up in the body. It manifests as objective and/or subjective sensory disorders in the distribution of the mental nerve or inferior alveolar nerve, represented primarily by half of the lower lip and chin. Although numb chin syndrome falls mainly within t...

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An Unusual Presentation of Plasma Cell Leukemia with Undiagnosed Multiple Myeloma

A 54 year old man with history of cardiomyopathy and chronic fibrillation first presented with bloody diarrhea. Then during the assessment of his abnormal lab. data revealed cast nephropathy in renal biopsy, gamma peak in protein electrophoresis and fine lytic lesions in skull graphy. His bone marrow asp...

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ژورنال

عنوان ژورنال: American Journal of Hematology

سال: 2002

ISSN: 0361-8609

DOI: 10.1002/ajh.10077